Homology Modelling of Human E1 Ubiquitin Activating Enzyme.
نویسندگان
چکیده
Human E1 is a key player in protein ubiquitination, however the E1 structure is not available. In this paper, we describe the derivation of a human E1 structure using molecular modelling based on the crystal structure of S. cerevisiae E1 and M. Musculus E1. Key interactions between our E1 model and ubiquitin are also discussed.
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عنوان ژورنال:
- Letters in drug design & discovery
دوره 7 1 شماره
صفحات -
تاریخ انتشار 2010